Jul 19, 2024 | Gabby’s followup preprint performing inhibitor screens against MET kinase libraries is now on biorXiv. Priyanka and I also published a review of an interesting recent preprint by Vincoff et al. which fine-tuned ESM-2 on fusion oncoproteins. Read it on PREreview: https://prereview.org/reviews/12658078 Finally, I just joined the organizing committee of the Atlas of Variant Effects seminar series. |
May 24, 2024 | We had a few papers published recently: our paper on the drug transporter OCT1 was published in Molecular Cell, and our Rosace paper was just published in Genome Biology. Also, Matt’s preprint on a proton-sensing GPCR is up on bioRxiv, as well as Gabby’s preprint on MET kinase fusions and activating mutations. |
Nov 11, 2023 | I was awarded an F32 through NIGMS for my proposal “Connecting structure and fitness landscapes to overcome antibiotic resistance.” |
Aug 25, 2023 | I received a Mary Anne Koda-Kimble Seed Award for Innovation to support my efforts for massively combinatorial library generation for transformative pharmacogenomics, with an exciting acronym: SHRIMPLE. |
Feb 26, 2023 | Samantha Martinez from the University of San Francisco spent the break in the lab working on a project with us, and gave a great presentation for the UCSF-USF internship program. Thanks for your hard work, Samantha! |
Sep 26, 2022 | I am giving a seminar at the University of San Francisco: “Breaking things to see how they work: predicting antibiotic resistance with massively parallel assays.” Thanks to Professors Janet Yang (USF) and Bassem Al-Sady (UCSF) for the opportunity! |
Sep 12, 2022 | Our review of the SMRs is online at JBC now: take a look! Still rocking in the structural era: a molecular overview of the Small Multidrug Resistance (SMR) transporter family |
Aug 19, 2022 | Alexis started her PhD program in Biophysics at Johns Hopkins University - congrats! |
Jul 27, 2022 | We just posted a preprint of our DMS library generation technique, DIMPLE. |
Mar 20, 2022 | I’m attending the Ligand Recognition and Molecular Gating Gordon Research conference and seminar in Italy! |
Feb 19, 2022 | I presented a poster at the 2022 Biophysical Society meeting. |
Sep 01, 2021 | I started my postdoctoral appointment in the Fraser Lab at UCSF! |